Erythromycin 500mg information - Erythrocin Tablets - Summary of Product Characteristics (SmPC) - (eMC)
Ask your doctor or pharmacist if you have questions.
erythromycin
Prepare your injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine. Shake 500mg oral suspension liquid before 500mg measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring information not a kitchen spoon. You must chew the chewable information before you swallow it.
Do not crush, chew, or break a delayed-release capsule or tablet. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve, erythromycin 500mg information.
Erythromycin doses can increase your risk of infection that is resistant to medication. Erythromycin information not treat a viral infection such as the flu or a common cold.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using erythromycin. Store at room temperature away from moisture, heat, erythromycin 500mg information, and light. Mild to moderate infection: Usual Adult Dose of Erythromycin for Chancroid: Usual Adult Dose for Lymphogranuloma Venereum: Usual Adult Dose for Mycoplasma Pneumonia: Usual Adult Dose for Otitis Media: Usual Adult Dose for Pharyngitis: Usual Adult Dose for Pneumonia: Usual Adult Dose for Syphilis -- Early: Usual Adult Dose for Bronchitis: Usual Adult Dose for Chlamydia Infection: Usual Adult Dose for Lyme Disease: Usual Adult Dose for Legionella Pneumonia: Erythromycin was previously recommended by the American Heart Association for prophylaxis prior to 500mg, oral and upper respiratory tract erythromycin in at-risk, penicillin-allergic patients.
It is no longer erythromycin because of the high incidence of gastrointestinal adverse effects and complicated pharmacokinetics of the various formulations. However, patients who have successfully received erythromycin for prophylaxis in the past may continue with this regimen if desired, erythromycin 500mg information. Currently, clindamycin, first-generation cephalosporins in patients who have not had an IgE-mediated anaphylactic reaction to penicillinazithromycin 500mg clarithromycin are drugs of choice for prophylaxis in penicillin-allergic patients undergoing oral, dental, respiratory tract or esophageal procedures.
Usual Adult Dose for Bowel 500mg Erythromycin is recommended by the American Heart Association for long-term prophylaxis of streptococcal upper respiratory tract infections in the prevention of recurrences of rheumatic fever in patients allergic to penicillin and sulfonamides.
Usual Pediatric Dose for Bowel Preparation: Usual Pediatric Dose for Pneumonia: Neonatal chlamydial conjunctivitis and pneumonia: Usual Pediatric Dose for Chlamydia Infection: Usual Pediatric Dose for Pertussis: For women who cannot tolerate this regimena erythromycin dose of mg, by mouth, 4 times a day should be used for at information 14 days, erythromycin 500mg information.
For adults with uncomplicated urethral, endocervical, or rectal infections caused by Chlamydia trachomatis in whom tetracyclines are contraindicated or not tolerated: Nongonococcal urethritis due to Ureaplasma urealyticum When tetracycline is contraindicated or not tolerated: Acute pelvic inflammatory disease due to N gonorrhoeae erythromycin IV of erythromycin lactobionate for information, USP every 6 hours for 3 days followed by mg of erythromycin, orally every six hours for 7 days.
The pellets are colored white and orange. Capsules are supplied in bulk containers of 75, NDC Prevention of Rheumatic Fever.
They include nauseavomiting, abdominal paindiarrhea and anorexia. Allergic reactions ranging from urticaria to anaphylaxis have occurred. Skin reactions ranging from mild eruptions to erythema multiforme, Stevens-Johnson syndromeand toxic epidermal necrolysis have been reported rarely, erythromycin 500mg information. There have been reports of interstitial nephritis coincident with erythromycin use. There have been reports of pancreatitis and convulsions.
There have been isolated reports of reversible hearing loss occurring chiefly in patients with renal insufficiency levitra uk pharmacy in patients receiving high doses of erythromycin. There have been published reports suggesting that when oral erythromycin is given concurrently with theophylline there is a significant decrease in erythromycin serum concentrations of approximately 35 percent. The mechanism by which this interaction occurs is unknown.
The decrease in erythromycin concentrations due to coadministration of information could result in subtherapeutic concentrations of erythromycin. Hypotensionbradyarrhythmias, and lactic acidosis have been observed in patients receiving concurrent erythromycin, belonging to the calcium channel blockers drug class.
Concomitant administration of erythromycin and digoxin has been reported to result in elevated digoxin serum levels. There have been reports of increased anticoagulant effects information erythromycin and oral anticoagulants were used concomitantly.
Increased anticoagulation effects due to interactions of erythromycin with oral anticoagulants may be more pronounced in the elderly. Co-administration of erythromycin and a drug primarily metabolized by CYP3A may be associated with elevations in drug concentrations that could increase or prolong both the therapeutic and adverse effects of the concomitant drug.
Dosage adjustments may be considered, and when possible, serum concentrations of drugs primarily metabolized by CYP3A should be monitored closely in patients concurrently receiving erythromycin.
The following are examples of some clinically significant CYP3A based drug interactions. Interactions with erythromycin drugs metabolized by the CYP3A warfarin generic name brand name are also possible. The following CYP3A based drug interactions have been observed with erythromycin products in post-marketing experience: Triazolobenzodiazepines such as triazolam and alprazolam and related benzodiazepines Erythromycin has been reported to decrease the clearance of triazolam and midazolam, and thus, may increase the pharmacologic effect of these benzodiazepines.
500mg reports of rhabdomyolysis 500mg been reported in patients taking these drugs concomitantly. Sildenafil Viagra Erythromycon has been reported to increase the systemic exposure AUC of sildenafil.
Reduction of sildenafil dosage should be considered. See Viagra package insert. There have been spontaneous or published reports of CYP3A based interactions of erythromycin with carbamazepine, cyclosporine, tacrolimus, alfentanil, disopyramide, bromocriptine, rifabutin, quinidine methylprednisolone, cilostazol, and vinblastine.
In addition, erythromycin 500mg information, there have been reports of interactions of erythromycin with drugs not thought to be metabolized by CYP3A, including hexobarbital, phenytoin, and valproate. Erythromycin has been reported to significantly alter the metabolism of the nonsedating antihistamines terfenadine and astemizole when taken concomitantly.
In addition, deaths have been reported rarely with concomitant administration of terfenadine and erythromycin. There have been post-marketing reports of drug interactions when erythromycin was coadministered with cisapride, resulting in QT prolongation, cardiac arrhythmias, ventricular tachycardiaventricular fibrillationand torsades de pointes, most likely due to the inhibition of hepatic metabolism of cisapride by erythromycin.
Erythromycin
Erythromycin is considered a moderate inhibitor of CYP3A4. A significant increase in colchicine plasma concentration is anticipated when co-administered with moderate CYP3A4 inhibitors such as erythromycin.
If co-administration of colchicine and erythromycin is necessary, the information dose of colchicine may need to be reduced, and the maximum colchicine dose should be lowered. QT Prolongation Erythromycin has been associated with prolongation of the QT interval and infrequent cases of arrhythmia, erythromycin 500mg information. Cases of torsades de pointes have been spontaneously reported during postmarketing surveillance in patients receiving erythromycin. Fatalities have been reported.
Erythromycin should be avoided in patients with known erythromycin of the QT interval, erythromycin 500mg information, patients with ongoing proarrhythmic conditions such as uncorrected hypokalemia or hypomagnesemiaclinically significant bradycardiaand in patients receiving Class IA quinidine, procainamide or Class III dofetilide, 500mg, sotalol antiarrhythmic agents.
Elderly patients may be more susceptible to drug-associated effects on the QT interval. Syphilis in pregnancy There have been erythromycin suggesting that erythromycin does not reach the fetus in adequate concentration to prevent congenital syphilis. Infants born to women treated during information with oral erythromycin for early syphilis should be treated with an appropriate penicillin regimen.
Clostridium difficile-associated diarrhea Clostridium difficile-associated diarrhea CDAD erythromycin been reported with use of 500mg all antibacterial agents, including 500mg Capsules, erythromycin 500mg information, and may information in severity from mild diarrhea to fatal colitis.
ERYTHROMYCIN 500MG TABLETS
Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. Hypertoxin producing strains of C. CDAD must be considered in all patients who present with diarrhea 500mg antibiotic use.
Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents. Appropriate fluid and electrolyte management, protein supplementation, erythromycin 500mg information, antibiotic treatment of C, erythromycin 500mg information.
500mg Interactions Serious adverse reactions have been reported in patients taking erythromycin concomitantly with CYP3A4 substrates, erythromycin 500mg information. There have been post-marketing reports of colchicine toxicity with concomitant use 500mg erythromycin and colchicine.
Rhabdomyolysis with or erythromycin renal impairment has been reported in seriously ill patients receiving erythromycin erythromycin with lovastatin. Therefore, patients receiving concomitant lovastatin and erythromycin should be carefully monitored for information kinase CK and serum transaminase levels. See package insert for lovastatin. Exacerbation of symptoms of myasthenia gravis and new information of symptoms of myasthenic syndrome has been reported in patients receiving erythromycin therapy.
There have been reports of infantile hypertrophic pyloric stenosis IHPS occurring in infants following erythromycin therapy. In one cohort of newborns who were given erythromycin for pertussis prophylaxis, seven neonates 5 percent developed symptoms of non bilious vomiting or irritability with feeding and were subsequently diagnosed as having IHPS requiring surgical pyloromyotomy.
A possible dose-response effect was described with an absolute risk of IHPS of 5. Parents should be informed to contact their physician if vomiting or irritability with feeding occurs. Prolonged or erythromycin use of erythromycin may information in an overgrowth of nonsusceptible bacteria or fungi.
If superinfection occurs, erythromycin should be discontinued and appropriate therapy instituted, erythromycin 500mg information.
When indicated, incision and drainage or other surgical procedures should be 500mg in conjunction with antibiotic therapy. Infantile hypertrophic pyloric stenosis after pertussis information with erythromycin: The Lancet ; Carcinogenesis, erythromycin 500mg information, Mutagenesis and Impairment of Fertility Long-term 2-year oral studies conducted in rats with erythromycin base did not provide erythromycin of tumorigenicity. Mutagenicity studies have not been conducted, erythromycin 500mg information.
There was no apparent effect on male or female fertility in rats fed erythromycin base at levels up to 0. There was no evidence of teratogenicity or any other adverse information on reproduction in female rats fed erythromycin base 500mg to 0.
Erythromycin Stearate
There are, erythromycin 500mg information, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are 500mg always predictive of human response, this drug should be used during pregnancy only if clearly needed. Labor and Delivery The information of erythromycin erythromycin labor and delivery is unknown.
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